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Caution should be observed when HYTRIN tablets are administered concomitantly with other antihypertensive agentsespecially the calcium channel blocker verapamilto avoid the possibility of developing significant hypotensionWhen using HYTRIN tablets and other antihypertensive agents concomitantlydosage reduction and retitration of either agent may be necessarysee PRECAUTIONSHypotension has been reported when Hytrin has been used with phosphodiesterase-5PDE-5inhibitors.
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Read the Patient Information Leaflet if available from your pharmacist before you start taking terazosin and each time you get a refillIf you have any questionsask your doctor or pharmacist.
Pharmacokinetic studies indicate that patients with impaired renal function need no alteration in the recommended dosages.
The terazosin dose should be titrated with particular caution in patients with impaired liver function since terazosin undergoes extensive hepatic metabolism and is mainly excreted by the biliary tractAs no clinical experience is available in patients with severe hepatic impairmentthe use of terazosin is not recommended in these patients.
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