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Like other diureticsindapamide can cause hypokalemialow potassiumand hypomagnesemialow magnesiumThese changes can increase the risk of digoxinLanoxintoxicitypossibly resulting in fatal abnormal heart rhythmsUse of amiodaroneCordaroneand indapamide also can lead to cardiac arrhythmiasThe ability of the kidney to eliminate lithiumLithobidEskalithis decreased in patients receiving diureticsincluding indapamideThe use of these two drugs together could result in lithium toxicity.

Take this medication by mouth with or without food as directed by your doctorusually once daily in the morningIf you take this drug too close to bedtimeyou may need to wake up to urinateIt is best to take this medication at least 4 hours before your bedtime.

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